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Tuesday, November 30, 2021

Researchers announce needle-free vaccine patches coming soon

Efforts have been doubled-down on by researchers in an attempt to develop needle-free vaccine patches which can deliver medication painlessly through the skin.

A new study published in the Journal Science Advances has revealed promising results. Skin patches may help with vaccine distribution as they don’t require cold-chain requirements and might increase vaccine efficacy.


The one square centimetre patches are dotted with over 5,000 microscopic spikes. These spikes are coated with an experimental vaccine and the patch is clicked on with an applicator that resembles a honey puck.

When the patch was trialled on mice along with the syringe vaccine it was discovered that those who got the patch produced higher levels of antibodies after two doses.

According to a Virologist at the University of Queensland ‘David Muller’, a sub-group of mice who were only administered one dose of the vaccine containing a substance called an adjuvant, which spurs an immune response, didn’t get sick at all.


Mr. Muller stated that the tiny spikes on the patches cause localised skin death which alerts the body to an issue and triggers a greater immune response than injecting into a patient’s muscle.

In terms of storage, the patch can be stable for at least 30 days at 25C and one week at 40C, compared to the Moderna and Pfizer vaccines which can only be stable at room temperature for a few days.

Human trials for the patch are expected to begin in April with two American companies ‘Vaxess’ and ‘Micron Biomedical’ joining ‘Vaxxas’ in producing the patch.

IMAGE – “201214-D-BN624-0811” (CC BY 2.0) by U.S. Secretary of Defense


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